Publications
- 05/27/2021 - Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection
- 05/23/2021 - Anti-PD-1 in combination with Trametinib suppresses tumor growth and improves survival of intrahepatic cholangiocarcinoma in mice
- 05/11/2021 - ZBP1 not RIPK1 mediates tumor necroptosis in breast cancer
- 04/26/2021 - Genome sequence, transcriptome, and annotation of rodent malaria parasite Plasmodium yoelii nigeriensis N67
- 04/01/2021 - Low-level variant calling for non-matched samples using a position-based and nucleotide-specific approach
- 04/01/2021 - Small-Molecule natural product Physachenolide C potentiates immunotherapy efficacy by targeting BET proteins
- 04/01/2021 - Distinct biomarker profiles and TCR sequence diversity characterize the response to PD-L1 blockade in a mouse melanoma model
- 03/01/2021 - Gene editing rescues in vitro T cell development of RAG2-deficient induced pluripotent stem cells in an artificial thymic organoid system
- 03/01/2021 - Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol
- 03/01/2021 - TIGIT expression on CD8+ T cells correlates with higher cytotoxic capacity
- 03/01/2021 - APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
- 02/28/2021 - Inhibition of adjuvant-induced TAM receptors potentiates cancer vaccine immunogenicity and therapeutic efficacy
- 02/24/2021 - Iterative epigenomic analyses in the same single cell
- 02/08/2021 - TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers
- 02/01/2021 - Ubiquitination of MHC Class II by March-I regulates dendritic cell fitness
- 01/06/2021 - Differential expression of Triggering Receptor Expressed on Myeloid cells 2 (Trem2) in tissue eosinophils
- 01/05/2021 - Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer
- 01/01/2021 - Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms
- 01/01/2021 - HLA alleles B*53:01 and C*06:02 are associated with higher risk of P. falciparum parasitemia in a cohort in Uganda
- 12/01/2020 - Genome-wide screens identify lineage- and tumor-specific genes modulating MHC-I- and MHC-II-restricted immunosurveillance of human lymphomas
- 11/09/2020 - Antigenic re-stimulation of virus-specific memory CD8 T Cells requires days of lytic protein accumulation for maximal cytotoxic capacity
- 11/01/2020 - Association of Inhibitory Killer Cell Immunoglobulin-like Receptor Ligands with higher Plasmodium falciparum parasite prevalence
- 10/23/2020 - Inborn errors of Type I IFN immunity in patients with life-threatening COVID-19
- 10/16/2020 - A germline 1;3 translocation disrupting the VHL gene: a novel genetic cause for von Hippel-Lindau
- 10/01/2020 - Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients
- 10/01/2020 - Host gene expression modulated by Zika virus infection of human-293 cells
- 09/01/2020 - Whole-Exome Profiling of NSCLC Among African Americans
- 09/01/2020 - The genomic landscape of Mongolian hepatocellular carcinoma
- 09/01/2020 - GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma and APOBEC3B is directly transcriptionally regulated by GATA3
- 09/01/2020 - The mutational landscape of histiocytic sarcoma associated with lymphoid malignancy
- 08/12/2020 - Glycolytic metabolism of pathogenic T cells enables early detection of GvHD by 13C-MRI
- 08/01/2020 - Protein kinase A inhibitor proteins (PKIs) divert GPCR-G?s-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth
- 07/28/2020 - Induction of phenotypic changes in HER2-postive breast cancer cells in vivo and in vitro
- 07/01/2020 - Single-cell–derived primary rectal carcinoma cell lines reflect intratumor heterogeneity associated with treatment response
- 06/19/2020 - Evaluation of the anti-tumor activity of the humanized monoclonal antibody NEO-201 in preclinical models of ovarian cancer
- 06/01/2020 - Drugs targeting tumor-initiating cells prolong survival in a post-surgery, post-chemotherapy ovarian cancer relapse model
- 06/01/2020 - Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization
- 05/01/2020 - Impact of losing hRpn13 Pru or UCHL5 on proteasome clearance of ubiquinated proteins and RA190 cytoxicity
- 03/01/2020 - An analytical pipeline for identifying and mapping the integration sites of HIV and other retroviruses
- 02/01/2020 - Mosaicism for KCNJ5 causing early-onset primary Aldosteronism due to bilateral Adrenacortical Hyperplasia
- 01/14/2020 - Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template
- 01/01/2020 - The RepID-CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation
- 01/01/2020 - Case Report: single-cell transcriptomic analysis of an anaplastic oligodendroglioma post immunotherapy
- 12/01/2019 - Radiation drives the evolution of orthotopic xenografts initiated from glioblastoma stem-like cells
- 12/01/2019 - Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans
- 11/01/2019 - CRISPR/Cas9-mediated knockout and in situ inversion of the ORF57 gene from all copies of the Kaposi's Sarcoma-Associated Herpesvirus genome in BCBL-1 cells
- 09/01/2019 - Intestinal PPAR? Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6
- 08/01/2019 - Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups
- 08/01/2019 - Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels
- 05/01/2019 - Relationship between human leukocyte antigen alleles and risk of Kaposi's sarcoma in Cameroon
- 04/01/2019 - Single chromosome anaeuploidy induces genome-wide perturbation of nuclear organization and gene expression
- 01/01/2019 - Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness
- 01/01/2019 - Distinct genome-wide methylation patterns in sporadic and hereditary nonfunctioning pancreatic neuroendocrine tumors
- 01/01/2019 - Papillomavirus can be transmitted through the blood and produce infections in blood recipients: Evidence from two animal models
- 12/01/2018 - Discovery of Kaposi’s sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA
- 11/01/2018 - Murine pre-B-cell ALL induces T-cell dysfunction not fully reversed by introduction of a chimeric antigen receptor
- 11/01/2018 - NPHS2 V260E is a frequent cause of steroid-resistant nephrotic syndrome in Black South African children
- 10/01/2018 - Metastatic adrenocortical carcinoma displays higher mutation rate and tumor heterogeneity than primary tumors
- 09/01/2018 - Fetal-not maternal APOL1 genotype associated with risk for preeclampsia in those with African ancestry
- 04/01/2018 - ONC201 kills breast cancer cells in vitro by targeting mitochondria
- 04/01/2018 - Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis
- 02/01/2018 - 5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox
- 02/01/2018 - Genomic heterogeneity within individual prostate cancer foci impacts predictive biomarkers of targeted therapy
- 01/01/2018 - Identification of Casz1 as a Regulatory Protein Controlling T Helper Cell Differentiation, Inflammation, and Immunity
- 01/01/2018 - HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways
- 01/01/2018 - CD47 Expression in Natural Killer Cells Regulates Homeostasis and Modulates Immune Response to Lymphocytic Choriomeningitis Virus
- 12/01/2017 - Attenuation of Myeloid-Specific TGF? Signaling Induces Inflammatory Cerebrovascular Disease and Stroke
- 12/01/2017 - Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer
- 12/01/2017 - NF?B Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells
- 11/01/2017 - TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance
- 09/01/2017 - Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer
- 09/01/2017 - Identification of novel RNA isoforms of LMNA
- 08/01/2017 - Identification of essential genes for cancer immunotherapy
- 02/01/2017 - Circulating tumor cells capture disease evolution in advanced prostate cancer
- 01/01/2017 - Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma
- 10/01/2016 - Chronic expression of interferon-gamma leads to murine autoimmune cholangitis with a female predominance
- 10/01/2016 - O-GlcNAcase Is an RNA Polymerase II Elongation Factor Coupled to Pausing Factors SPT5 and TIF1?
- 06/17/2016 - Twist1 and Slug mediate H2AX-regulated epithelial-mesenchymal transition in breast cells
- 06/01/2016 - Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype
- 05/01/2016 - Identification of an Immunogenic Subset of Metastatic Uveal Melanoma