Publications
- 11/01/2022 - Distinct roles of treatment schemes and BRCA2 on the restoration of homologous recombination DNA repair and PARP inhibitor resistance in ovarian cancer
- 10/28/2022 - RAS oncogene signal strength regulates matrisomal gene expression and tumorigenicity of mouse keratinocytes
- 09/27/2022 - Immunogenetics associated with severe coccidioidomycosis
- 09/06/2022 - Loss of CD47 alters CD8+ T cell activation in vitro and immunodynamics in mice
- 06/27/2022 - Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell Carcinoma
- 06/21/2022 - Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence
- 05/18/2022 - Antisense transcription from lentiviral gene targeting linked to an integrated stress response in colorectal cancer cells
- 05/09/2022 - A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers
- 04/12/2022 - Triple combination of BET plus PI3K and NF-?B inhibitors exhibit synergistic activity in adult T-cell leukemia/lymphoma
- 03/01/2022 - A phase 2 study of Pembrolizumab in combination with Capecitabine and Oxaliplatin with molecular profiling in advanced biliary tract carcinoma
- 03/01/2022 - Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-? signaling enables PD-L1-mediated tumor eradication
- 02/11/2022 - Reusable single cell for iterative epigenomic analyses
- 02/01/2022 - H3K27ac nucleosomes facilitate HMGN localization at regulatory sites to modulate chromatin binding of transcription factors
- 02/01/2022 - Urine single-cell RNA sequencing in focal segmental glomerulosclerosis reveals inflammatory signatures
- 12/16/2021 - Characterization of HLH-like manifestations as a CRS variant in patients receiving CD22 CAR T cells
- 12/14/2021 - TNF plays a crucial role in inflammation by signaling via T cell TNFR2
- 12/01/2021 - Identifying and characterizing virus-encoded circular RNAs
- 12/01/2021 - The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation
- 11/17/2021 - Protein-RNA interactome analysis reveals wide association of KSHV ORF57 with host non-coding RNAs and polysomes
- 11/01/2021 - PERK signaling through C/EBP? contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells
- 11/01/2021 - TP53 loss initiates chromosomal instability in fallopian tube epithelial cells
- 10/20/2021 - Ecdysoneless protein regulates viral and cellular mRNA splicing to promote cervical oncogenesis
- 10/07/2021 - CTCF is a barrier for totipotent 2C-like reprogramming
- 10/01/2021 - The ETS transcription factor ERF controls the exit from the naïve pluripotent state in a MAPK-dependent manner
- 09/16/2021 - ASXL1 and STAG2 are common mutations in GATA2 deficiency patients with bone marrow disease and myelodysplastic syndrome
- 09/09/2021 - Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing
- 09/01/2021 - Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing
- 08/01/2021 - Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape
- 07/14/2021 - Severe COVID-19 is characterized by an impaired type I interferon response and elevated levels of arginase producing granulocytic myeloid derived suppressor cells
- 06/30/2021 - Characterizing expression and regulation of Gamma-Herpesviral circular RNAs
- 05/27/2021 - Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection
- 05/23/2021 - Anti-PD-1 in combination with Trametinib suppresses tumor growth and improves survival of intrahepatic cholangiocarcinoma in mice
- 05/11/2021 - ZBP1 not RIPK1 mediates tumor necroptosis in breast cancer
- 04/26/2021 - Genome sequence, transcriptome, and annotation of rodent malaria parasite Plasmodium yoelii nigeriensis N67
- 04/01/2021 - Low-level variant calling for non-matched samples using a position-based and nucleotide-specific approach
- 04/01/2021 - Small-Molecule natural product Physachenolide C potentiates immunotherapy efficacy by targeting BET proteins
- 04/01/2021 - Distinct biomarker profiles and TCR sequence diversity characterize the response to PD-L1 blockade in a mouse melanoma model
- 03/01/2021 - Gene editing rescues in vitro T cell development of RAG2-deficient induced pluripotent stem cells in an artificial thymic organoid system
- 03/01/2021 - Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol
- 03/01/2021 - TIGIT expression on CD8+ T cells correlates with higher cytotoxic capacity
- 03/01/2021 - APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
- 02/28/2021 - Inhibition of adjuvant-induced TAM receptors potentiates cancer vaccine immunogenicity and therapeutic efficacy
- 02/24/2021 - Iterative epigenomic analyses in the same single cell
- 02/08/2021 - TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers
- 02/01/2021 - Ubiquitination of MHC Class II by March-I regulates dendritic cell fitness
- 01/06/2021 - Differential expression of Triggering Receptor Expressed on Myeloid cells 2 (Trem2) in tissue eosinophils
- 01/05/2021 - Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer
- 01/01/2021 - Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms