iPathwayGuide is a gene and protein expression analysis tools that uses a systems biology approach to identify significantly impacted pathways, gene ontology terms, diseases, and predicted microRNAs based on the given gene or protein differential expression signature. iPathwayGuide uses the most advanced pathway analysis approach that considers the role, positioning, and relationships of a given gene within a pathway, resulting in a significant reduction in false positives associated with pathway analysis. Perform next-gen pathway analysis using Advaita’s proprietary “Impact Analysis” method to identify significant pathways without the noise found in other approaches. Simple, easy, web-based application.