Publications
- 12/14/2021 - TNF plays a crucial role in inflammation by signaling via T cell TNFR2
- 12/01/2021 - Identifying and characterizing virus-encoded circular RNAs
- 12/01/2021 - The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation
- 11/17/2021 - Protein-RNA interactome analysis reveals wide association of KSHV ORF57 with host non-coding RNAs and polysomes
- 11/01/2021 - PERK signaling through C/EBP? contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells
- 11/01/2021 - TP53 loss initiates chromosomal instability in fallopian tube epithelial cells
- 10/20/2021 - Ecdysoneless protein regulates viral and cellular mRNA splicing to promote cervical oncogenesis
- 10/07/2021 - CTCF is a barrier for totipotent 2C-like reprogramming
- 10/01/2021 - The ETS transcription factor ERF controls the exit from the naïve pluripotent state in a MAPK-dependent manner
- 09/16/2021 - ASXL1 and STAG2 are common mutations in GATA2 deficiency patients with bone marrow disease and myelodysplastic syndrome
- 09/09/2021 - Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing
- 09/01/2021 - Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing
- 08/01/2021 - Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape
- 07/14/2021 - Severe COVID-19 is characterized by an impaired type I interferon response and elevated levels of arginase producing granulocytic myeloid derived suppressor cells
- 06/30/2021 - Characterizing expression and regulation of Gamma-Herpesviral circular RNAs
- 05/27/2021 - Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection
- 05/23/2021 - Anti-PD-1 in combination with Trametinib suppresses tumor growth and improves survival of intrahepatic cholangiocarcinoma in mice
- 05/11/2021 - ZBP1 not RIPK1 mediates tumor necroptosis in breast cancer
- 04/26/2021 - Genome sequence, transcriptome, and annotation of rodent malaria parasite Plasmodium yoelii nigeriensis N67
- 04/01/2021 - Low-level variant calling for non-matched samples using a position-based and nucleotide-specific approach
- 04/01/2021 - Small-Molecule natural product Physachenolide C potentiates immunotherapy efficacy by targeting BET proteins
- 04/01/2021 - Distinct biomarker profiles and TCR sequence diversity characterize the response to PD-L1 blockade in a mouse melanoma model
- 03/01/2021 - Gene editing rescues in vitro T cell development of RAG2-deficient induced pluripotent stem cells in an artificial thymic organoid system
- 03/01/2021 - Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol
- 03/01/2021 - TIGIT expression on CD8+ T cells correlates with higher cytotoxic capacity
- 03/01/2021 - APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
- 02/28/2021 - Inhibition of adjuvant-induced TAM receptors potentiates cancer vaccine immunogenicity and therapeutic efficacy
- 02/24/2021 - Iterative epigenomic analyses in the same single cell
- 02/08/2021 - TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers
- 02/01/2021 - Ubiquitination of MHC Class II by March-I regulates dendritic cell fitness
- 01/06/2021 - Differential expression of Triggering Receptor Expressed on Myeloid cells 2 (Trem2) in tissue eosinophils
- 01/05/2021 - Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer
- 01/01/2021 - Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms
- 01/01/2021 - HLA alleles B*53:01 and C*06:02 are associated with higher risk of P. falciparum parasitemia in a cohort in Uganda
- 12/01/2020 - Genome-wide screens identify lineage- and tumor-specific genes modulating MHC-I- and MHC-II-restricted immunosurveillance of human lymphomas
- 11/09/2020 - Antigenic re-stimulation of virus-specific memory CD8 T Cells requires days of lytic protein accumulation for maximal cytotoxic capacity
- 11/01/2020 - Association of Inhibitory Killer Cell Immunoglobulin-like Receptor Ligands with higher Plasmodium falciparum parasite prevalence
- 10/23/2020 - Inborn errors of Type I IFN immunity in patients with life-threatening COVID-19
- 10/16/2020 - A germline 1;3 translocation disrupting the VHL gene: a novel genetic cause for von Hippel-Lindau
- 10/01/2020 - Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients
- 10/01/2020 - Host gene expression modulated by Zika virus infection of human-293 cells
- 09/01/2020 - Whole-Exome Profiling of NSCLC Among African Americans
- 09/01/2020 - The genomic landscape of Mongolian hepatocellular carcinoma
- 09/01/2020 - GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma and APOBEC3B is directly transcriptionally regulated by GATA3
- 09/01/2020 - The mutational landscape of histiocytic sarcoma associated with lymphoid malignancy
- 08/12/2020 - Glycolytic metabolism of pathogenic T cells enables early detection of GvHD by 13C-MRI
- 08/01/2020 - Protein kinase A inhibitor proteins (PKIs) divert GPCR-G?s-cAMP signaling toward EPAC and ERK activation and are involved in tumor growth
- 07/28/2020 - Induction of phenotypic changes in HER2-postive breast cancer cells in vivo and in vitro
- 07/01/2020 - Single-cell–derived primary rectal carcinoma cell lines reflect intratumor heterogeneity associated with treatment response
- 06/19/2020 - Evaluation of the anti-tumor activity of the humanized monoclonal antibody NEO-201 in preclinical models of ovarian cancer
- 06/01/2020 - Drugs targeting tumor-initiating cells prolong survival in a post-surgery, post-chemotherapy ovarian cancer relapse model
- 06/01/2020 - Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization
- 05/01/2020 - Impact of losing hRpn13 Pru or UCHL5 on proteasome clearance of ubiquinated proteins and RA190 cytoxicity
- 03/01/2020 - An analytical pipeline for identifying and mapping the integration sites of HIV and other retroviruses
- 02/01/2020 - Mosaicism for KCNJ5 causing early-onset primary Aldosteronism due to bilateral Adrenacortical Hyperplasia
- 01/14/2020 - Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template
- 01/01/2020 - The RepID-CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation
- 01/01/2020 - Case Report: single-cell transcriptomic analysis of an anaplastic oligodendroglioma post immunotherapy
- 12/01/2019 - Radiation drives the evolution of orthotopic xenografts initiated from glioblastoma stem-like cells
- 12/01/2019 - Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans
- 11/01/2019 - CRISPR/Cas9-mediated knockout and in situ inversion of the ORF57 gene from all copies of the Kaposi's Sarcoma-Associated Herpesvirus genome in BCBL-1 cells
- 09/01/2019 - Intestinal PPAR? Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6
- 08/01/2019 - Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups
- 08/01/2019 - Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels